(Metformin 500mg + Glimepiride 1mg) is used to treat type 2 diabetes mellitus; when diet, exercise, and glimepiride or metformin alone are not able to control the blood sugar levels.
🛒 How to order this item?
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
Show More
During treatment with Amaryl M 1mg Tablet, it's advisable to avoid alcohol consumption. Alcohol can affect the blood sugar-lowering action of the medication and increase the risk of lactic acidosis.
Amaryl M 1mg Tablet should not be taken during pregnancy. If you're planning to become pregnant, consult your doctor before taking this medication.
Avoid taking Amaryl M 1mg Tablet during breastfeeding, as it may pass through breast milk. Seek advice from your doctor before using this medication.
If you experience symptoms of low or high blood sugar (dizziness, tiredness, shaking, trembling) or visual problems due to altered blood sugar levels, do not drive or operate machinery.
The medication is not recommended for use in patients with severe kidney disease. For those with kidney disease, the medication should be used with caution and your dose may need adjustment based on kidney function. Consult your doctor before taking Amaryl M 1mg Tablet if you have kidney issues.
Amaryl M 1mg Tablet is not recommended for use in individuals with severe liver disease. If you have liver disease, use the medication with caution, and your dose may need adjustment based on liver function. Consult your doctor before taking this medication if you have liver problems.
Glimepiride: This component not only lowers blood sugar levels but also stimulates the pancreas to release more insulin. Insulin is crucial as it helps transport sugar (glucose) from the blood into cells for energy.
Metformin: Its action includes enhancing the body's natural response to insulin, thereby improving the utilization of sugar by cells. It also decreases the liver's production of sugar. This dual mechanism results in better control over blood sugar levels.
This tablet is prescribed for individuals diagnosed with type 2 diabetes mellitus, serving as an adjunct to their diet and exercise regimen. It is particularly recommended in the following scenarios:
When monotherapy with either metformin or glimepiride proves ineffective in achieving the desired level of glycemic control.
As a replacement for the combination therapy of glimepiride and metformin, when necessary.
Glimepiride functions as a sulfonylurea antidiabetic agent, effectively lowering blood glucose levels. Its primary mechanism involves stimulating insulin release from functional pancreatic beta cells. Glimepiride collaborates with glucose, enhancing the sensitivity of beta cells to normal glucose stimuli, which leads to insulin secretion. Additionally, Glimepiride may affect liver glucose production, increase peripheral tissue sensitivity to insulin, and enhance glucose uptake. In non-fasting diabetic patients, a single dose of Glimepiride can sustain its hypoglycemic effect for 24 hours.
Metformin Hydrochloride belongs to the biguanide class of antihyperglycemic medications, utilized for type 2 diabetes treatment. It acts differently from sulfonylureas and doesn't induce hypoglycemia. Metformin Hydrochloride lowers both baseline and postprandial plasma glucose levels by reducing hepatic glucose synthesis and intestinal glucose absorption.
The dosage of this tablet is determined by the target blood glucose level. Initiate therapy with the lowest effective dose to achieve desired metabolic control. Regular blood and urine glucose monitoring is crucial during treatment. Avoid escalating doses due to errors like missed doses. Glimepiride dose might decrease over time due to increased insulin sensitivity with improved diabetes management. Timely dose reduction or cessation is vital to prevent hypoglycemia. Daily maximum: 8 mg glimepiride, 2000 mg metformin. The initial dose shouldn't exceed the current glimepiride/metformin daily doses to prevent hypoglycemia. Switching from separate glimepiride/metformin therapy must consider current dosage.
Administration: Take the Amaryl tablet whole, with liquid, before or during breakfast. Don't skip meals.
Overdose: Excessive intake may lead to hypoglycemia and lactic acidosis. Symptoms include nausea, restlessness, dizziness, etc. Seek medical attention and consume glucose/sugar products.
Missed Dose: Missing a dose could cause high blood sugar symptoms. Take missed doses as soon as remembered. If close to the next dose, skip and continue the regular schedule. Don't double dose.
Drug-Drug Interactions:
Drug-Food Interaction:
Drug-Disease Interactions:
As with any medication, it's essential to follow your healthcare provider's instructions carefully and to communicate openly about your medical history, current health status, and any other medications or supplements you might be taking. This will help your doctor make informed decisions about the suitability of Amaryl M 1mg Tablet for your specific circumstances and to minimize the risk of adverse effects or interactions. Always consult your healthcare professional before making any changes to your medication regimen.
Pregnancy:
Lactation:
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.